Fractional Flow Reserve and Coronary Computed Tomographic Angiography

Fractional Flow Reserve and Coronary Computed Tomographic Angiography

Background: Invasive Fractional Flow Reserve Obstructive coronary artery disease (CAD) produces symptoms and increases the risk of adverse cardiac outcomes. However, determining whether a particular coronary stenosis is responsible for causing myocardial ischemia can be challenging, even with invasive coronary angiography (ICA). To help guide decisions in the cardiac catheterization laboratory,...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Cost analysis of non-invasive fractional flow reserve derived from coronary computed tomographic angiography in Japan

Percutaneous coronary intervention (PCI) based on fractional flow reserve (FFRcath) measurement during invasive coronary angiography (CAG) results in improved patient outcome and reduced healthcare costs. FFR can now be computed non-invasively from standard coronary CT angiography (cCTA) scans (FFRCT). The purpose of this study is to determine the potential impact of non-invasive FFRCT on costs...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Based on review of available data, the Company may consider the use of noninvasive fractional flow reserve (FFR) following a positive coronary computed tomography angiography (CCTA) to guide decisions about the use of invasive coronary angiography (ICA) in patients with stable chest pain at intermediate risk of coronary artery disease (CAD i.e., suspected or presumed stable ischemic heart disea...

Coronary Computed Tomography Angiography with Selective Noninvasive Fractional Flow Reserve

Fractional flow reserve using coronary computed tomography angiography requires at least 64slice coronary computed tomography angiography and cannot be calculated when images lack sufficient quality (HeartFlow, 2013) (11% to 13% in recent studies; Koo et al, 2011; Min et al, 2012; Nakazato et al, 2013; Nørgaard et al, 2014), e.g., in obese individuals (e.g., body mass index, >35 kg/m2). The pre...